What is DELZICOL?

Learn more about DELZICOL

DELZICOL and Ulcerative Colitis How DELZICOL Works

If you have been diagnosed with mild-to-moderate ulcerative colitis (UC), it is likely your doctor will recommend a medicine called a mesalamine, also referred to as 5-aminosalicylic acid or 5-ASA, which is a common treatment for this type of UC.

DELZICOL has replaced Asacol (mesalamine), a leading 5-ASA for the last 20 years.1 In addition, an ingredient in the coating of DELZICOL, dibutyl phthalate (DBP), was replaced with dibutyl sebacate (DBS), which was an improvement in the formulation.

  • If your doctor previously prescribed Asacol, you can feel confident transitioning to DELZICOL because it is the improved formulation of Asacol.
  • DELZICOL works the same way as Asacol and is dosed in a similar fashion.

If you’ve been taking DELZICOL, you may have noticed the capsule has changed

Instead of one solid 400 mg capsule, there are four 100 mg tablets inside of one capsule that can be opened. While the active ingredient has not changed, and your DELZICOL should work the same, this capsule allows for patients as young as 5 years of age to adjust their dosage and take DELZICOL as well.

DELZICOL may help reduce symptoms associated with UC

  • DELZICOL was shown to reduce the rectal bleeding and stool frequency associated with mildly to moderately active UC in patients 5 years of age and older.2
  • DELZICOL was also shown to help maintain remission in adults with UC.3
    • "Remission" means that there was little or no inflammation in the patient's colon based on certain criteria by diagnostic evaluation* at the beginning of the study and 6 months later

    *proctosigmoidoscopy or colonoscopy.

Not Actual Size

DELZICOL may reduce the inflammation of UC

  • Ulcerative colitis can cause inflammation in the lining of the colon or large intestine4
  • DELZICOL is believed to reduce and calm this inflammation2,5

DELZICOL may help you relieve the symptoms of mild to moderate UC flares as part of a larger treatment plan to manage your condition.

If you are switching from a previous oral mesalamine therapy to DELZICOL, you should talk to your healthcare provider about discontinuing your previous oral mesalamine therapy and following the dosing instructions for DELZICOL.

  • Back to top
  • What if I take DELZICOL
  • Asacol is a registered trademark of Medeva Pharma Suisse AG, licensed to Allergan Pharmaceuticals International Limited.

    References

  • 1.
    IMS National Prescription Data: 1992-March 2014 (estimate derived from information used under license from IMS Health, Inc., which expressly reserves all rights, including rights of copying, distribution, and republication).
  • 2.
    Sninsky CA, Cort DH, Shanahan F, et al. Oral mesalamine (Asacol) for mildly to moderately active ulcerative colitis. Ann Intern Med. 1991;115:350-355.
  • 3.
    The Mesalamine Study Group. An oral preparation of mesalamine as long-term maintenance therapy for ulcerative colitis: a randomized, placebo-controlled trial. Ann Intern Med. 1996;124:204-211.
  • 4.
    Genetics Home Reference. Ulcerative colitis. http://ghr.nlm.nih.gov/condition/ulcerative-colitis. Accessed January 7, 2015.
  • 5.
    Delzicol [package insert]. Parsippany, NJ: Warner Chilcott (US), LLC; 2015.
  • See More Important Risk Information

    IMPORTANT RISK INFORMATION

    Who should not take DELZICOL?

    • Do not take DELZICOL if you are allergic to:
      • salicylates, such as aspirin or medications that contain aspirin
      • aminosalicylates
      • any of the ingredients of DELZICOL

    What should I tell my healthcare provider before taking DELZICOL?

    Tell your healthcare provider if you:

    • Have or have had kidney problems
    • Are allergic to sulfasalazine
    • Have or have had heart-related allergic reactions, such as inflammation of the heart muscle (myocarditis) or inflammation of the lining of the heart (pericarditis)
    • Have or have had liver problems
    • Have or have had a stomach blockage
    • Have any other medical conditions

    What are the possible side effects of DELZICOL?

    DELZICOL may cause serious side effects, including:

    • Kidney problems: Your doctor may check to see how your kidneys are working before taking DELZICOL. It is important to complete all blood tests ordered by your doctor.
    • A condition that may be hard to tell apart from a UC flare: Symptoms include cramping, stomachache, bloody diarrhea, and sometimes fever, headache, and rash. If you experience any of these symptoms while on treatment, call your doctor right away. He or she may tell you to stop taking DELZICOL.
    • Hypersensitivity (allergic) reactions: If signs and symptoms of hypersensitivity occur, immediately call your doctor.
    • Liver failure: In patients that have or have had liver disease.
    • Blood Disorders: Elderly patients and patients taking azathioprine or 6-mercaptopurine need to monitor complete blood cell counts and platelet counts while taking DELZICOL.

    The most common side effects of DELZICOL include:

    • Adults: belching, stomachache, constipation, dizziness, runny nose, back pain, rash, upset stomach, and flu symptoms.
    • Children (5 to 17 years of age): inflammation of the nose and pharynx, headache, stomachache, dizziness, inflammation of the sinuses, rash, cough, diarrhea, tiredness, fever, and increased lipase.

    Tell your doctor if you have any side effect that bothers you or does not go away. These are not all the possible side effects of DELZICOL.

    Before starting DELZICOL, tell your doctor about all medications you are taking, including:

    • Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen. Taking these medications with DELZICOL may increase your risk of kidney problems.
    • Azathioprine or 6-mercaptopurine. Taking these medications with DELZICOL may increase your risk of blood disorders.

    What is DELZICOL?

    DELZICOL (mesalamine) delayed-release capsules is a prescription medication approved for the treatment of mildly to moderately active ulcerative colitis (UC) in patients 5 years of age and older and for the maintenance of remission of UC in adults.

    Please see full Prescribing Information for DELZICOL.

    To report a side effect from one of our products, please call the Allergan Drug Safety Department at 1-800-678-1605.

    ×

    Thank you for visiting

    You are now leaving an Allergan website. A link to a non-Allergan website does not constitute an endorsement of the products or services offered by the non-Allergan website, and Allergan is not responsible for the content of any non-Allergan website.

    ×

    Terms, Conditions, and Eligibility Criteria: